American Cruise Line Cruises

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  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • Clarksville, Tennessee
    • Nashville, Tennessee
    Sailing Dates:
    • August 2025
    interior from
    Not Available
    oceanview from
    $3,795
    $542pernight
    balcony from
    $4,415
    $631pernight
    suite from
    $6,300
    $900pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 10%
    Riverview from $3,795
    ($542pernight)
    4.1 rating out of 5  (4 reviews)
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American Cruise Lines

  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • April 2025
    • May 2025
    • June 2025
    • July 2025
    • November 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    interior from
    Not Available
    oceanview from
    $3,795
    $542pernight
    balcony from
    $4,415
    $631pernight
    suite from
    $6,300
    $900pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 10%
    Riverview from $3,795
    ($542pernight)
    4.1 rating out of 5  (4 reviews)
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  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Music Cities

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • June 2025
    • July 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $3,860
    $551pernight
    balcony from
    $4,525
    $646pernight
    suite from
    $6,545
    $935pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,275 – Save up to 14%
    Riverview from $3,860
    ($551pernight)
    4.1 rating out of 5  (4 reviews)
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  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night The Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • River Cruising
    • Nashville, Tennessee
    Sailing Dates:
    • August 2026
    • September 2026
    interior from
    Not Available
    oceanview from
    $4,295
    $614pernight
    balcony from
    $4,915
    $702pernight
    suite from
    $6,800
    $971pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,295
    ($614pernight)
    4.1 rating out of 5  (4 reviews)
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  • American Independence
    4.6 rating out of 5  (8 reviews)

    7 Night Chesapeake Bay

    American Independence

    Departing from: Baltimore, Maryland
    Ports of Call:
    • Yorktown, Virginia
    • Crisfield, Maryland
    • Cambridge, Maryland
    • St. Michaels, Maryland
    • Annapolis, Maryland
    Sailing Dates:
    • May 2025
    • May 2026
    interior from
    Not Available
    oceanview from
    $4,925
    $704pernight
    balcony from
    $5,865
    $838pernight
    suite from
    $7,795
    $1,114pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $4,925
    ($704pernight)
    4.6 rating out of 5  (8 reviews)
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  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • April 2025
    • May 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $4,925
    $704pernight
    balcony from
    $5,740
    $820pernight
    suite from
    $7,790
    $1,113pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,240 – Save up to 8%
    Riverview from $4,925
    ($704pernight)
    4.9 rating out of 5  (7 reviews)
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  • American Constitution
    5 rating out of 5  (4 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constitution

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • April 2025
    • May 2025
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • September 2026
    • October 2026
    interior from
    Not Available
    oceanview from
    $5,100
    $729pernight
    balcony from
    $5,865
    $838pernight
    suite from
    $7,795
    $1,114pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $5,100
    ($729pernight)
    5 rating out of 5  (4 reviews)
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  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • July 2025
    • September 2025
    • April 2026
    • July 2026
    • September 2026
    • November 2026
    • December 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,165
    $595pernight
    suite from
    $6,050
    $864pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 15%
    Balcony from $4,165
    ($595pernight)
    3.5 rating out of 5  (5 reviews)
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  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Cleveland, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • River Cruising
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • July 2025
    • August 2025
    • November 2025
    • April 2026
    • July 2026
    • August 2026
    • November 2026
    • December 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,165
    $595pernight
    suite from
    $6,050
    $864pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $4,915 – Save up to 15%
    Balcony from $4,165
    ($595pernight)
    3.5 rating out of 5  (5 reviews)
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  • American Pride
    4.4 rating out of 5  (7 reviews)

    7 Night Columbia & Snake Rivers

    American Pride

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • April 2025
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    interior from
    Not Available
    oceanview from
    $5,155
    $736pernight
    balcony from
    $5,955
    $851pernight
    suite from
    $8,290
    $1,184pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,355 – Save up to 6%
    Riverview from $5,155
    ($736pernight)
    4.4 rating out of 5  (7 reviews)
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  • American Melody
    5 rating out of 5  (8 reviews)

    7 Night Lower Mississippi River

    American Melody

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Cleveland, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • River Cruising
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • April 2025
    • May 2025
    • November 2025
    • December 2025
    • April 2026
    • May 2026
    • November 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $4,775
    $682pernight
    suite from
    $6,795
    $971pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $5,275 – Save up to 9%
    Balcony from $4,775
    ($682pernight)
    5 rating out of 5  (8 reviews)
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  • American Harmony
    5 rating out of 5  (6 reviews)

    7 Night Columbia & Snake Rivers

    American Harmony

    Departing from: Portland, Oregon
    Ports of Call:
    • Hayden Island, Portland, Oregon
    • Astoria, Oregon
    • Mount St. Helens, Washington
    • Cruise Columbia River, Pacific Northwest, Usa
    • The Dalles, Oregon
    • Pendleton, Oregon
    • Cruise Snake River, Pacific Northwest, Usa
    • Clarkston, Washington
    Sailing Dates:
    • April 2025
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    $6,215
    $888pernight
    suite from
    $8,785
    $1,255pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $6,715 – Save up to 7%
    Balcony from $6,215
    ($888pernight)
    5 rating out of 5  (6 reviews)
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  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Southeast Alaska

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Petersburg, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Wrangell, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • May 2025
    • June 2025
    • July 2025
    • August 2025
    • September 2025
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    interior from
    Not Available
    oceanview from
    $6,400
    $914pernight
    balcony from
    $7,365
    $1,052pernight
    suite from
    $9,780
    $1,397pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from $6,400
    ($914pernight)
    4.9 rating out of 5  (7 reviews)
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  • American Constellation
    4.9 rating out of 5  (7 reviews)

    10 Night Alaskan Explorer

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Cruise Inside Passage, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Sitka, Alaska
    • Wrangell, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Petersburg, Alaska
    • Cruise Inside Passage, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • June 2025
    • July 2025
    • August 2025
    • June 2026
    • July 2026
    • August 2026
    interior from
    Not Available
    oceanview from
    $8,275
    $828pernight
    balcony from
    $9,665
    $967pernight
    suite from
    $13,100
    $1,310pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $10,665 – Save up to 9%
    Riverview from $8,275
    ($828pernight)
    4.9 rating out of 5  (7 reviews)
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  • American Constellation
    4.9 rating out of 5  (7 reviews)

    14 Night Alaska Inside Passage

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise Queen Charlotte Sound, British Columbia
    • Cruise Inside Passage, Alaska
    • Ketchikan, Alaska
    • Wrangell, Alaska
    • Petersburg, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    • Cruise Glacier Bay National Park
    • Haines, Alaska
    • Skagway, Alaska
    • Juneau, Alaska
    Sailing Dates:
    • May 2025
    • May 2026
    interior from
    Not Available
    oceanview from
    $9,200
    $657pernight
    balcony from
    $10,730
    $766pernight
    suite from
    $14,455
    $1,033pernight
    Rewards & Bonus Offers:
    • Cruises.com Rewards = Free Cash! Earn 10 points per $1 spent
    • Complimentary Dining, Cocktail Parties and More
     
    Was $11,730 – Save up to 9%
    Riverview from $9,200
    ($657pernight)
    4.9 rating out of 5  (7 reviews)
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American Cruise Line River Cruises

Enjoy exceptional value when you book discount American Cruise Line River cruises and discount river cruises with Cruises.com. Act now for the best deals on American Cruise Line river cruises and sail away with bonus offers that include free onboard spending, free cabin upgrades and more. Plus, discount American Cruise Line River cruises include all meals, accommodations, and countless onboard activities. Plan your river cruise vacation before these American Cruise Line deals are gone.

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